Dysbiosis: Causes, Consequences, and Surprising Facts

Author: Tata Grabovska

~ 5 min read

28 April 2025

Why Has Dysbiosis Become a Key Health Topic in the 21st Century?

Disruption of the gut microbiota balance — dysbiosis — today extends beyond a localized digestive issue. It is a complex condition that can potentially affect a wide range of body systems — from immunity to cognitive function. Cutting‑edge research is uncovering new ways to understand its causes and strategies for microbiome support. Let’s examine the key aspects of this phenomenon.

What Is Dysbiosis?

Dysbiosis is the disturbance of the natural equilibrium between beneficial and potentially harmful microorganisms in the digestive system. A healthy microbiome supports digestion, vitamin synthesis, metabolic processes, and immune balance. Losing that balance may trigger a range of physiological discomforts and health changes.

Primary Risk Factors for Microbiota Disruption

1. Medication Impact:

  • Antibiotics. Even short courses can significantly alter microbiota composition for extended periods.
  • Proton Pump Inhibitors (PPIs). Acid‑reducing drugs can promote overgrowth of pathogens such as Clostridium difficile.
  • Nonsteroidal Anti‑Inflammatory Drugs (NSAIDs). Ibuprofen and diclofenac can weaken the gut’s protective barrier, creating conditions favorable for imbalance.
  • Artificial Sweeteners. Aspartame, sucralose, and others can negatively affect microbiota composition by reducing levels of beneficial bacteria.

2. Western‑Style Diet:
Diets high in ultra‑processed foods, excess sugar, and low in fiber lead to reduced microbiome diversity and favor pathogenic strains.

3. Psychophysiological Factors:
Chronic stress and sleep deprivation directly alter the microbiome—these changes can occur in as little as three days and are comparable in effect to a high‑risk diet.

Debunking Common Myths

  • Myth 1: Dysbiosis is only a localized gut problem.
    Fact: Microbiota imbalance is linked to the immune, nervous, and endocrine systems, affecting allergies, autoimmune reactions, chronic inflammation, and emotional well‑being.

  • Myth 2: Probiotics are the only treatment for dysbiosis.
    Fact: Restoring balance requires a comprehensive strategy, including dietary correction, reducing risk factors (like antibiotics and stress), and supporting both prebiotics and microbiota.
  • Myth 3: All probiotics are the same.
    Fact: Probiotic selection must be personalized—different strains perform differently and interact uniquely with an individual’s microbiome and medications.

How to Recognize Dysbiosis?

Typical symptoms:

  • Irregular bowel habits: constipation, diarrhea, or a feeling of incomplete evacuation.
  • Gas and bloating after meals.
  • Abdominal rumbling and discomfort.

Extraintestinal signs:

  • Skin rashes, dryness, allergic reactions.
  • Persistent bad breath despite good oral hygiene.
  • Chronic fatigue, weakness, nutrient deficiencies (hair loss, brittle nails).
  • Frequent fungal infections due to reduced local immunity.

When Should You See a Doctor?

  • Symptoms persist for more than 1–2 weeks.
  • Presence of blood in stool, severe pain, or fever.
  • Unexplained weight loss.

Greespi — A Modern Approach to Gut Health Support

Greespi is a high‑tech functional product designed for comprehensive support of microbiota and overall gut health.

Greespi benefits:

  • Contains up to 71 % protein with a complete amino acid profile.
  • Natural sources of organic iron, calcium, magnesium, vitamin B12, and chlorophyll.
  • High bioavailability — up to 95 %, with minimal risk of discomfort or bloating.
  • Supports immunity and microbiota, promoting balance restoration.

Learn how Greespi combats dysbiosis here.

Ease of use:
Two servings per day help fill micronutrient gaps without complex diets or quality concerns.

Understanding, Not Moralizing

Avoiding vegetables or healthy behaviors is not simply laziness or negligence. Food choices are influenced by complex biological, psychological, and social factors.

Greespi offers an adaptive, science‑based solution that works effectively in a world where traditional diets often fail to provide adequate support.

References:

  1. Yang, S., Liu, H., & Liu, Y. (2025). Understanding dysbiosis and resilience in the human gut microbiome: biomarkers, interventions, and challenges. Frontiers in Microbiology, 16, 1559521.

  2. Zimmerman, E. S. (2019). Study of intestinal dysbiosis: state of the problem and new trends. Pancreatic Club Bulletin, 45(4), 44–53.

  3. Healthyliving.gr. (2021). Nutritional and medical applications of spirulina microalgae. Retrieved from [source].

  4. Hernandez-Saavedra, D., et al. (2024). The impact of processing on the nutritional quality of plant proteins. Food Research International, 146, 110589.

Wang, Y., et al. (2019). Polysaccharide from Spirulina platensis ameliorates diphenoxylate-induced constipation by modulating intestinal microbiota in mice. Food Research International, 125, 108625.

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