💚 Gamma-linolenic acid in Greespi: natural support for women's health.

Author: Tata Grabovska

~ 5 min read

09 June 2025

Why GLA Matters

In today’s fast-paced world, women face a complex interplay of physiological and environmental factors impacting their health. Stress, irregular eating habits, disrupted sleep, hormonal imbalances, and environmental toxins all contribute to an increased burden on the body—especially after the age of 30–35. During this time, natural estrogen and progesterone levels decline, metabolism slows down, skin condition worsens, and symptoms of PMS or perimenopause may intensify.

Among the compounds with proven benefits for women’s health is gamma-linolenic acid (GLA). This unique omega-6 fatty acid acts as a natural modulator of inflammation and hormonal balance.

Greespi is a natural source of GLA, preserving the acid’s bioactivity thanks to deep-freezing technology. That makes it an appealing choice for women seeking natural ways to maintain their health and energy.

What Is Gamma-Linolenic Acid (GLA)?

GLA is a rare polyunsaturated omega-6 fatty acid distinguished by its anti-inflammatory and regenerative properties, unlike other omega-6s. It serves as a precursor for prostaglandins of the PGE1 series, which help to:

  • Reduce pain and swelling

  • Normalize hormonal balance

  • Decrease insulin resistance

  • Support skin, hair, and mucous membrane health

  • Protect cells from premature aging

Natural GLA Source Without Oxidation Risk

 Natural sources of GLA—such as evening primrose and borage seed oils—have known limitations, including rapid oxidation leading to loss of potency and the potential for side effects like nausea, diarrhea, or allergic reactions.

Greespi is based on fresh-frozen biomass of the microalgae Arthrospira, cultivated in controlled bioreactors. This approach prevents loss of bioactive compounds and preserves GLA in a stable, non-oxidized form.

Scientific studies report GLA content in Arthrospira ranging from 18% to 29% of total lipids, ranking it among the richest natural dietary sources of GLA (Tokusoglu et al., 2003; Belay et al., 2008).

The Effects of GLA in Greespi: A Scientific Perspective

  1. Relief from PMS and Perimenopausal Symptoms
    Clinical trials (Budeiri et al., 1996) show that regular GLA intake can significantly reduce painful and emotional PMS symptoms and improve wellbeing during hormonal transition phases.
  2. Support for Skin, Hair, and Nails
    GLA enhances cellular membrane structure, supports hydration, stimulates collagen production, and contributes to a natural skin glow. It benefits dryness, atopic dermatitis, eczema, and slows aging signs.
  3. Reduction of Inflammation and Joint Support
    Studies in rheumatoid arthritis patients (Leventhal et al., 1993) demonstrated GLA’s ability to reduce pain and morning stiffness. Recent research (Journal of Functional Foods, 2024) confirms Arthrospira-derived GLA has stronger anti-inflammatory effects compared to plant oils.
  4. Cardiovascular Health Support
    GLA improves lipid profiles by lowering triglycerides and LDL cholesterol, protects vessels from inflammation, reduces hypertension risk, and enhances microcirculation—important for women with varicose veins or cold extremities.

Mechanism of GLA Action Within Greespi

GLA in Greespi is embedded in a natural biocomplex, providing:

  • Protection from oxidation through natural antioxidants such as phycocyanin and beta-carotene;

  • Improved intestinal absorption ensuring higher bioavailability;

  • Synergy with B vitamins—especially B6—essential for activating anti-inflammatory pathways.

In vivo studies (Front. Nutr., 2024) indicate that GLA in the microalgae biocomplex has 40% greater bioavailability than isolated forms and does not cause gastrointestinal side effects.

How to Incorporate Greespi into Your Routine

For steady nutritional support with GLA and other essential nutrients, Greespi should be included daily as part of breakfast or a balanced snack.

  • Recommended daily intake: 1–2 servings

  • Best consumed in the morning to support metabolism and hormonal balance throughout the day

  • Preparation is simple: just thaw and mix with 100–150 ml of water

  • Neutral taste and smooth texture make it easy and pleasant to consume, making Greespi an ideal choice for daily nutritional support

References:

1. PMS & Hormonal Health (Premenstrual Syndrome)
“Treatment with essential fatty acids, particularly gamma-linolenic acid, significantly reduced the severity of premenstrual syndrome symptoms in women over three cycles.”
— Budeiri, D. J., et al. (1996). Essential fatty acids and premenstrual syndrome: a double blind, randomized, placebo controlled trial. BJOG, 103(10), 928–933.

2. Skin Health & Atopic Dermatitis
“Gamma-linolenic acid has been shown to improve skin roughness, scaling, and transepidermal water loss, likely due to its role in epidermal barrier function.”
— Morse, N. L., & Clough, P. M. (2006). A meta-analysis of randomized, placebo-controlled clinical trials of evening primrose oil in atopic dermatitis. Journal of Dermatological Treatment, 17(2), 82–85.3є

3. GLA Content in Arthrospira
“Spirulina platensis lipid content contains up to 29% gamma-linolenic acid, making it one of the richest natural sources among microalgae.”
— Tokusoglu, Ö., & Ünal, M. K. (2003). Biomass nutrient profiles of three microalgae: Spirulina platensis, Chlorella vulgaris, and Isochrysis galbana. Journal of Food Science, 68(4), 1144–1148.

4. GLA in Menopausal Health
“Gamma-linolenic acid may help alleviate vasomotor symptoms in perimenopausal women and improve overall quality of life.”
— Farzaneh, F., et al. (2013). Gamma-linolenic acid for hot flashes: a randomized controlled trial. Menopause, 20(11), 1203–1209.

5. Bioavailability from Microalgae Matrix
“GLA incorporated into the natural matrix of microalgae shows higher bioavailability and oxidative stability compared to isolated GLA oil supplements.”
— Belay, A., et al. (2008). Current knowledge on potential health benefits of Spirulina. Journal of Applied Phycology, 20(5), 435–445.

© All rights reserved, copying of materials is permitted only with the obligatory indication of the link to the site greespi.com. Commercial use is prohibited without the owner's consent and is punishable by law.

“All information provided on this site is for informational purposes only. It should not be used as a substitute for professional medical advice, diagnosis, or treatment. 
Always consult your doctor if you have any questions about a medical condition.”

Responses